Pharmaceutical Use Stephania Epigaea Extract Rotundine 98% / Tetrahydropalmatine (L-THP)

Specification of Stephania Epigaea Extract Rotundine

[Production Name]: Stephania Epigaea Extract Rotundine

[Latin Name]: Estephania epigaea L.

[Apperance]: Yellpw brown to white fine powder

[Specification]:

Rotundine : 98%;

Stephania Epigaea Powder;

Ratio product: 5:1-20:1.

[Test Method]: HPLC /TLC

What is Stephania Epigaea Extract ?

Epigeal Srephaia Root Extract Can promote bone marrow tissue hyperplasia and increase white blood cells. Used for leucopenia. Can make the peripheral blood leukocytosis, animal studies found that can obviously prevent mitomycin cause a decrease in white cells, but not inhibit mitomycin anti-cancer effect. The mechanism of action is to promote bone marrow tissue hyperplasia, which elevated white blood cell function. Used for tumor chemotherapy, radiation therapy, cause granulocytopenia and other causes of leucopenia.

What is Tetrahydropalmatine (THP) / Rotundine?

Tetrahydropalmatine (THP) is an alkaloid found in several different plant species,mainly in the Corydalis family, but also in other plants such as Stephania rotunda.These plants have traditional uses in Chinese herbal medicine.

Tetrahydropalmatine has been demonstrated to possess analgesic effects and may be beneficial in the treatment of heart disease and liver damage. It is a blocker of voltage-activated L type calcium channel active potasium channels.It is a potent muscle relaxant.

Animal experiments have shown that the sedative effect of THP results from blocking dopaminergic neurons in the brain.Dopamine is an important neurotransmitter in the central nervous system where it occurs in severalimportant signalingsystems that regulate muscular activity and attention, as well as feelings of joy, enthusiasm and creativity.Therefore, THP causes no feelings of euphoria, and has been seen as an alternative to addictive drugs for people suffering from anxiety and pain, and as a possibility for relief for people not helped by existing drugs.

Faction of Stephania Epigaea Extract Rotundine

1. It can make the peripheral blood leukocytosis, promote bone marrow tissue hyperplasia;
2. It used to treatment thrombocytopenic purpura,
3. stephania element and salvia miltiorrhiza combined treatment of pneumoconiosis curative effect observation.

Application of Stephania Epigaea Extract Rotundine

1. Pharmaceutical Product;

2. Healthcare product.